In order to achieve low-carbon hydrogen production under diversified demands, a comprehensive energy management method based on hydrogen energy hub is proposed. Firstly, a comprehensive energy system management framework is constructed considering new energy units, electrochemical energy storage, gas generator units, hydrogen energy hubs and hydrogen loads. Then, based on the oxygen complementary utilization principle of hydrogen production by water electrolysis and rural biomass gasification, the design of hydrogen hub is introduced and the optimal operation model of hydrogen hub is established. Based on the energy management framework of the integrated energy system and the hydrogen energy hub model, the energy optimization management model of the integrated energy system is established, considering the constraints of hydrogen supply and demand balance, power balance, and operating characteristics of each equipment, in order to achieve efficient, economical, and environmentally friendly hydrogen production and energy management under diversified hydrogen demand. Finally, the numerical simulation of an integrated energy system with hydrogen energy hub verifies the effectiveness of the proposed method.